PGC-based genome editing has established itself as a robust and versatile platform in poultry science. This review chronicles the technological evolution from early untargeted …
We developed a biosensor using Pyrococcus furiosus Argonaute (PfAgo) for the highly sensitive and specific detection of single-nucleotide mutations causing fungicide resistance. …
Using CUT&Tag sequencing, we mapped the genome-wide binding sites of the transcription factor MEF2A in chicken primary myoblasts, identifying 1,768 target genes involved in …
We investigated the tissue expression and functional characteristics of the calcitonin (CT) family peptides and their receptors in chickens. Our findings reveal distinct …
In conclusion, we cloned the full-length sequence of chicken MC5R gene and characterized its promoter activity in DF1 chicken embryonic fibroblasts. The functional assay …
In summary, we cloned NPS and NPSR1 genes from the chicken brain. Functional assays proved the cNPSR1 can be potently activated by its endogenous ligand NPS and trigger multiple …
In summary, the full-length cDNA of the three chicken 5-HT receptor genes (HTR1B, HTR1E, and HTR1F) were first reported in the present study. Sequence alignment showed that the …
In summary, our data sets a critical reference point to reveal the novel aspects of pituitary biology across vertebrates, and helps to figure out how the anterior pituitary, as a …
In addition, we found that pig MRAP2 can decrease surface expression, increase the ligand sensitivity and selectivity of pMC4RAsp/pMC4RAsn, and enhance the basal constitutive …
In summary, we cloned six genes of the MC4R signaling system in a representative teleost species, Nile tilapia. Functional study proved that MC4R can interact with MRAP2b and …