In summary, we proved that AVT possesses four functional receptors (AVPR1A, AVPR1B, AVPR2b and MTR), and MT has a single receptor (MTR).
In summary, we characterized two APLNRs in chickens and turtles, and three APLNRs in zebrafish.
The orphan receptor GPR25 was cloned from zebrafish, pigeons and spotted gars. GPR25 is activated by Apelin and Apela in non-mammalian vertebrates. Like Apelin receptor, GPR25 is …
Collectively, our data helps to elucidate the physiological roles of NMU/NMS peptides in birds and reveal the functional conservation and changes of NMU/NMS-NMUR axis across …
In summary, we revealed an intricate interaction network of MC4R/MC3R with α-MSH/ACTH, AgRP and MRAP2 (/MRAP) in chickens.
Taken together, our study offers novel information about the expression and functionality of cY1, cY4, cY6 and their ligands in birds, and helps to decipher their conserved roles …
On the whole, our data establishes a molecular basis to elucidate the actions of three functional NPY receptors (cY2, cY5 and cY7) and their ligands in birds, which helps to …
Taken together, our findings raise a novel concept that the actions of SCFAs are likely mediated by 2 FFA2s (FFA2 and FFA2L) in target tissues of some mammalian species, such as …